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Journal article

The inwardly rectifying K+ channel KIR7.1 controls uterine excitability throughout pregnancy.

Abstract:

Abnormal uterine activity in pregnancy causes a range of important clinical disorders, including preterm birth, dysfunctional labour and post-partum haemorrhage. Uterine contractile patterns are controlled by the generation of complex electrical signals at the myometrial smooth muscle plasma membrane. To identify novel targets to treat conditions associated with uterine dysfunction, we undertook a genome-wide screen of potassium channels that are enriched in myometrial smooth muscle. Comput...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.15252/emmm.201403944

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Publisher:
EMBO Press Publisher's website
Publication date:
2014-01-01
DOI:
EISSN:
1757-4684
ISSN:
1757-4676
Source identifiers:
477605

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