Journal article
Phylogenetic analysis indicates that Evasin-like proteins of Ixodid ticks fall into three distinct classes
- Abstract:
-
Chemokines are structurally related proteins that activate leucocyte migration in response to injury or infection. Tick saliva contains chemokine-binding proteins or evasins which likely neutralize host chemokine function and inflammation. Biochemical characterisation of 50 evasins from Ixodes, Amblyomma and Rhipicephalus shows that they fall into two functional classes, A and B, with exclusive binding to either CC- or CXC- chemokines, respectively. Class A evasins, EVA1 and EVA4 have a four-...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
British Heart Foundation
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Bibliographic Details
- Publisher:
- Frontiers Media Publisher's website
- Journal:
- Frontiers in Cellular and Infection Microbiology Journal website
- Volume:
- 11
- Article number:
- 769542
- Publication date:
- 2021-10-22
- Acceptance date:
- 2021-09-24
- DOI:
- EISSN:
-
2235-2988
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
1203312
- Local pid:
- pubs:1203312
- Deposit date:
- 2021-10-18
Terms of use
- Copyright holder:
- Bhattacharya and Nuttall.
- Copyright date:
- 2021
- Rights statement:
- ©2021 Bhattacharya and Nuttall. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
- Licence:
- CC Attribution (CC BY)
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