Journal article
Intensive lowering of LDL cholesterol with 80 mg versus 20 mg simvastatin daily in 12,064 survivors of myocardial infarction: a double-blind randomised trial.
- Abstract:
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Background
Lowering of LDL cholesterol reduces major vascular events, but whether more intensive therapy safely produces extra benefi ts is uncertain. We aimed to establish effi cacy and safety of more intensive statin treatment in patients at high cardiovascular risk.
Methods
We undertook a double-blind randomised trial in 12 064 men and women aged 18–80 years with a history of myocardial infarction. Participants were either currently on or had clear indication fo...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Access Document
- Files:
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(Version of record, pdf, 405.6KB)
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- Publisher copy:
- 10.1016/s0140-6736(10)60310-8
Authors
Funding
Medical Research Council
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British Heart Foundation
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Merck
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Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- Lancet (London, England) Journal website
- Volume:
- 376
- Issue:
- 9753
- Pages:
- 1658-1669
- Publication date:
- 2010-11-08
- DOI:
- EISSN:
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1474-547X
- ISSN:
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0140-6736
Item Description
- Language:
- English
- Keywords:
- Pubs id:
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pubs:97244
- UUID:
-
uuid:ce0a580d-7862-469b-94c7-112a96907644
- Local pid:
- pubs:97244
- Source identifiers:
-
97244
- Deposit date:
- 2012-12-19
Terms of use
- Copyright holder:
- Elsevier
- Copyright date:
- 2010
- Notes:
- Copyright © 2010 Elsevier Ltd. Open Access funded by British Heart Foundation
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