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Journal article

Blood pressure and cerebral white matter share common genetic factors in Mexican Americans

Abstract:

Elevated arterial pulse pressure and blood pressure (BP) can lead to atrophy of cerebral white matter (WM), potentially attributable to shared genetic factors. We calculated the magnitude of shared genetic variance between BP and fractional anisotropy of water diffusion, a sensitive measurement of WM integrity in a well-characterized population of Mexican Americans. The patterns of whole-brain and regional genetic overlap between BP and fractional anisotropy were interpreted in the context th...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
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Publisher:
American Heart Association Publisher's website
Journal:
Hypertension Journal website
Volume:
57
Issue:
2
Pages:
330-335
Publication date:
2011-02-01
DOI:
EISSN:
1524-4563
ISSN:
0194-911X
Source identifiers:
445994
Language:
English
Keywords:
Subjects:
Pubs id:
pubs:445994
UUID:
uuid:cfa342b3-7cb8-492b-8bc2-13835388c733
Local pid:
pubs:445994
Deposit date:
2014-01-18

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