Journal article
The role of TASK-like K+ channels in oxygen sensing in the carotid body.
- Abstract:
-
The carotid body plays an important role in initiating protective responses to hypoxemia. The primary oxygen sensing cells are the glomus or type 1 cells. Hypoxia evokes the secretion of neurotransmitters from these cells which then excite afferent nerves. This response is mediated via membrane depolarization and voltage-gated Ca2+ entry. Studies from this laboratory have revealed that membrane depolarization in response to hypoxia is primarily the result of inhibition of background K+ channe...
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Bibliographic Details
- Journal:
- Novartis Foundation symposium
- Volume:
- 272
- Pages:
- 73-140
- Publication date:
- 2006-01-01
- EISSN:
-
1935-4657
- ISSN:
-
1528-2511
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:312265
- UUID:
-
uuid:d00bf588-0fdb-4f4a-8c42-d455c45c1398
- Local pid:
- pubs:312265
- Source identifiers:
-
312265
- Deposit date:
- 2013-11-17
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- Copyright date:
- 2006
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