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Investigating modifications to participant information materials to improve recruitment into a large randomized trial.

Abstract:

Background: Large randomized trials are the best method to test the efficacy and safety of treatments expected to have moderate effects. We observed a significant decline in potential participants’ response to mailed invitations to participate in such trials over a 10-year period and investigated possible reasons behind this and potential modifications to the invitation process to mitigate it.

Methods: Participants who declined to pa...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/s13063-019-3779-4

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Role:
Author
ORCID:
0000-0002-1179-0023
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Medical Research Council More from this funder
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Grant:
SP/14/3/31114
SP/08/010/25939
Publisher:
BioMed Central Publisher's website
Journal:
Trials Journal website
Volume:
20
Article number:
681
Publication date:
2019-12-05
Acceptance date:
2019-10-09
DOI:
EISSN:
1745-6215
Pmid:
31805983

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