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Adiponectin as a regulator of vascular redox state in human atherosclerosis

Abstract:

Atherosclerotic cardiovascular disease is a leading cause of death worldwide. Dysregulation of vascular redox state plays a crucial role in the atherosclerotic process. Increased production of vascular superoxide (O2·-) and other reactive oxygen species (ROS) leads to endothelial dysfunction, a key early step in atherogenesis. Adipose tissue is a source of vasoactive, hormone-like molecules which are termed adipokines. One of the most important adipokines is adiponectin. Adiponectin has been ...

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Division:
MSD
Department:
Cardiovascular Medicine
Role:
Author

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Supervisor
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Supervisor
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Supervisor
British Heart Foundation More from this funder
Medical Research Council More from this funder
Research Council UK More from this funder
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
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UUID:
uuid:d0fe8c70-17b2-4462-8961-87f36815f85d
Deposit date:
2017-05-23

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