Thesis
Adiponectin as a regulator of vascular redox state in human atherosclerosis
- Abstract:
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Atherosclerotic cardiovascular disease is a leading cause of death worldwide. Dysregulation of vascular redox state plays a crucial role in the atherosclerotic process. Increased production of vascular superoxide (O2·-) and other reactive oxygen species (ROS) leads to endothelial dysfunction, a key early step in atherogenesis. Adipose tissue is a source of vasoactive, hormone-like molecules which are termed adipokines. One of the most important adipokines is adiponectin. Adiponectin has been ...
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Authors
Contributors
+ Antoniades, C
Role:
Supervisor
+ Casadei, B
Role:
Supervisor
+ Channon, K
Role:
Supervisor
Funding
British Heart Foundation
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Medical Research Council
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Research Council UK
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Bibliographic Details
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
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uuid:d0fe8c70-17b2-4462-8961-87f36815f85d
- Deposit date:
- 2017-05-23
Related Items
Terms of use
- Copyright holder:
- Margaritis, M
- Copyright date:
- 2016
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