Journal article
Activity-dependent spinal cord neuromodulation rapidly restores trunk and leg motor functions after complete paralysis
- Abstract:
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Epidural electrical stimulation (EES) targeting the dorsal roots of lumbosacral segments restores walking in people with spinal cord injury (SCI). However, EES is delivered with multielectrode paddle leads that were originally designed to target the dorsal column of the spinal cord. Here, we hypothesized that an arrangement of electrodes targeting the ensemble of dorsal roots involved in leg and trunk movements would result in superior efficacy, restoring more diverse motor activities after t...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Access Document
- Files:
-
-
(Accepted manuscript, pdf, 23.3MB)
-
- Publisher copy:
- 10.1038/s41591-021-01663-5
Authors
Bibliographic Details
- Publisher:
- Springer Nature Publisher's website
- Journal:
- Nature Medicine Journal website
- Volume:
- 28
- Issue:
- 2
- Pages:
- 260-271
- Publication date:
- 2022-02-07
- Acceptance date:
- 2021-12-16
- DOI:
- EISSN:
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1546-170X
- ISSN:
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1078-8956
- Pmid:
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35132264
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
1310894
- Local pid:
- pubs:1310894
- Deposit date:
- 2023-01-25
Terms of use
- Copyright holder:
- Rowald et al.
- Copyright date:
- 2022
- Rights statement:
- © 2022, The Author(s), under exclusive licence to Springer Nature America, Inc.
- Notes:
- This is the accepted manuscript version of the article. The final version is available from Springer Nature at: 10.1038/s41591-021-01663-5
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