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A genome-wide association search for type 2 diabetes genes in African Americans.

Abstract:

African Americans are disproportionately affected by type 2 diabetes (T2DM) yet few studies have examined T2DM using genome-wide association approaches in this ethnicity. The aim of this study was to identify genes associated with T2DM in the African American population. We performed a Genome Wide Association Study (GWAS) using the Affymetrix 6.0 array in 965 African-American cases with T2DM and end-stage renal disease (T2DM-ESRD) and 1029 population-based controls. The most significant SNPs ...

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Publication status:
Published

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Publisher copy:
10.1371/journal.pone.0029202

Authors


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General Clinical Research Center of the Wake Forest University School of Medicine More from this funder
Johns Hopkins University More from this funder
Center for Inherited Disease Research More from this funder
National Institutes of Health More from this funder
Publisher:
Public Library of Science Publisher's website
Journal:
PloS one Journal website
Volume:
7
Issue:
1
Article number:
e29202
Publication date:
2012-01-04
DOI:
EISSN:
1932-6203
Source identifiers:
270663

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