A fictitious domain approach for hybrid simulations of eukaryotic chemotaxis

Thesis

Chemotaxis, the phenomenon through which cells respond to external chemical signals, is one of the most important and universally observable in nature. It has been the object of considerable modelling effort in the last decades. The models for chemotaxis available in the literature cannot reconcile the dynamics of external chemical signals and the intracellular signalling pathways leading to the response of the cells. The reason is that models used for cells do not contain the distinction ...

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Authors: Seguis, J

• Publication date: 2013
• Type of award: DPhil
• Level of award: Doctoral
• Awarding institution: University of Oxford
• Language: English
• Keywords: Finite Elements; Fictitious domain method; PDEs; Chemotaxis
• Subjects: Biology and other natural sciences (mathematics); Numerical analysis; Computer science (mathematics); Mathematical biology; Functional analysis (mathematics); Partial differential equations