Journal article
CD8+ T cells specific for conserved, cross-reactive Gag epitopes with strong ability to suppress HIV-1 replication
- Abstract:
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Background: Development of AIDS vaccines for effective prevention of circulating HIV-1 is required, but no trial has demonstrated definitive effects on the prevention. Several recent T-cell vaccine trials showed no protection against HIV-1 acquisition although the vaccines induced HIV-1-specific T-cell responses, suggesting that the vaccine-induced T cells have insufficient capacities to suppress HIV-1 replication and/or cross-recognize circulating HIV-1. Therefore, it is necessary to develop...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 4.3MB)
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- Publisher copy:
- 10.1186/s12977-018-0429-y
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Authors
Funding
Bibliographic Details
- Publisher:
- BioMed Central Publisher's website
- Journal:
- Retrovirology Journal website
- Volume:
- 15
- Publication date:
- 2018-07-03
- Acceptance date:
- 2018-06-25
- DOI:
- EISSN:
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1742-4690
- Pmid:
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29970102
- Source identifiers:
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869710
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:869710
- UUID:
-
uuid:d5a9efa7-06b7-4fd6-bf1e-f81b70a5f03a
- Local pid:
- pubs:869710
- Deposit date:
- 2018-08-30
Terms of use
- Copyright holder:
- Murakoshi et al
- Copyright date:
- 2018
- Notes:
-
© The Author(s) 2018. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License
(http://creat iveco mmons .org/licen ses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium,
provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license,
and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creat iveco mmons .org/
publi cdoma in/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
- Licence:
- CC Attribution (CC BY)
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