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Thesis

Understanding P450 hydroxylation profiles

Abstract:

The enzymatic approach to C-H functionalisation is a promising field within contemporary organic chemistry that complements parallel advances with chemical reagents. The cytochrome P450BM3, refined through aeons of evolution, offers a sustainable and elegant methodology for achieving synthetically valuable hydroxylations at ubiquitous C-H sites. This opens the potential for new synthetic strategies, relying on early-, mid- or late-stage C-H functionalisation. Gaining a working ...

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Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author

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Role:
Supervisor
Type of award:
MSc by Research
Level of award:
Masters
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
Deposit date:
2021-02-25

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