Thesis
Data-driven approaches to fragment merging
- Abstract:
-
The COVID-19 pandemic provided stark evidence of the need for robust drug development pipelines that allow the rapid discovery and advancement of therapeutics such as antivirals. Increasing the pace with which we develop diverse compounds during the early stages of the pipeline is central to addressing problems of attrition and improving the efficiency of drug discovery.
Fragment-based drug discovery (FBDD) emerged as an alternative to the more established high-throughput screening,...
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Authors
Contributors
+ Deane, C
- Institution:
- University of Oxford
- Division:
- MPLS
- Department:
- Statistics
- Role:
- Supervisor
- ORCID:
- 0000-0003-1388-2252
+ von Delft, F
- Institution:
- University of Oxford
- Role:
- Supervisor
+ Sanchez-Garcia, R
- Role:
- Supervisor
+ Hubbard, R
- Role:
- Supervisor
+ Roughley, S
- Role:
- Supervisor
+ Engineering and Physical Sciences Research Council
More from this funder
- Funder identifier:
- https://ror.org/0439y7842
- Grant:
- EP/S024093/1
- Programme:
- EPSRC CDT in Sustainable Approaches to Biomedical Science: Responsible and Reproducible Research - SABS:R^3
- DOI:
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- Language:
-
English
- Keywords:
- Subjects:
- Deposit date:
-
2025-10-26
Terms of use
- Copyright holder:
- Stephanie Wills
- Copyright date:
- 2024
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