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Actin regulation in activity-dependent synaptic plasticity at the Drosophila neuromuscular junction

Abstract:

Synaptic plasticity is the process by which synaptic connections are continuously modified and is the molecular basis of learning and memory. These modifications require new protein synthesis and cytoskeletal rearrangements at or near the synapse. Syncrip, an mRNA-binding protein, is conserved from Drosophila to vertebrates and is found to regulate mRNAs encoding proteins required in synaptic plasticity. Many of these proteins have functions in actin-binding, actin cytoskeleton organizatio...

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Division:
MSD
Department:
Biochemistry
Role:
Author

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Role:
Supervisor
Role:
Supervisor
Type of award:
MSc by Research
Level of award:
Masters
Awarding institution:
University of Oxford

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