Thesis
Hydrogen Sulfide (H2S) as a regulator of myocardial redox state and the redox-sensitive regulation of cystathionine γ-lyase (CSE)
- Abstract:
-
In advanced stages, cardiac disease causes millions of deaths each year. Superoxide anions (O2.-) and their derivative peroxynitrite (ONOO-) contribute to cardiac disease pathogenesis, yet strategies to reduces these reactive oxygen species through antioxidants in large scale clinical trials have largely been unsuccessful. Better understanding of pathways regulating enzymatic sources of O2.- like NADPH oxidases, uncoupled nitric oxide ...
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Authors
Contributors
+ Antoniades, C
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Supervisor
+ Casadei, B
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Supervisor
Funding
+ The University of Oxford Radcliffe Department of Medicine (RDM) Scholars Programme
More from this funder
Funding agency for:
Tarun, A
Bibliographic Details
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:d866892d-ed0c-4995-b8c2-5c71657e7774
- Deposit date:
- 2018-07-19
Terms of use
- Copyright holder:
- Tarun, A
- Copyright date:
- 2017
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