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Journal article

Behavioural discrimination of noxious stimuli in infants is dependent on brain maturation

Abstract:

Changes in facial expression are an essential form of social communication and in nonverbal infants are often used to alert care providers to pain-related distress. However, studies of early human brain development suggest that premature infants aged less than 34 weeks' gestation do not display discriminative brain activity patterns to equally salient noxious and innocuous events. Here we examine the development of facial expression in 105 infants, aged between 28 and 42 weeks' gestation. We ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1097/j.pain.0000000000001425

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Paediatrics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Paediatrics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Paediatrics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Paediatrics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Humanities Division
Department:
Philosophy
Role:
Author
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More from this funder
Funding agency for:
Wilkinson, D
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Publisher:
Lippincott, Williams & Wilkins Publisher's website
Journal:
Pain Journal website
Volume:
160
Issue:
2
Pages:
493–500
Publication date:
2018-11-12
Acceptance date:
2018-09-04
DOI:
EISSN:
1872-6623
ISSN:
0304-3959
Keywords:
Pubs id:
pubs:919069
UUID:
uuid:d954665c-8b3d-430b-9726-71a3e9038be8
Local pid:
pubs:919069
Deposit date:
2018-09-13

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