Journal article
Fractalkine promotes human monocyte survival via a reduction in oxidative stress.
- Abstract:
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OBJECTIVE: The CX3C chemokine fractalkine (CX3CL1) has a critical role in the development of atherogenesis because apolipoprotein-E-deficient mice lacking CX3CL1 or its receptor CX3CR1 develop smaller plaques and polymorphisms in CX3CR1 are associated with altered risk of cardiovascular disease. CX3CR1 is found on numerous cell types involved in atherogenesis but seems to have a key role in monocyte function. We aimed to elucidate the role of CX3CL1 in human monocyte survival and determine th...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 849.1KB)
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- Publisher copy:
- 10.1161/atvbaha.114.304717
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Authors
Funding
Bibliographic Details
- Publisher:
- American Heart Association Publisher's website
- Journal:
- Arteriosclerosis, thrombosis, and vascular biology Journal website
- Volume:
- 34
- Issue:
- 12
- Pages:
- 2554-2562
- Publication date:
- 2014-12-01
- DOI:
- EISSN:
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1524-4636
- ISSN:
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1079-5642
- Source identifiers:
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488359
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:488359
- UUID:
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uuid:dac033ce-d24d-4086-9713-f8a204d5bcbf
- Local pid:
- pubs:488359
- Deposit date:
- 2014-11-15
Terms of use
- Copyright holder:
- White et al
- Copyright date:
- 2014
- Notes:
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Copyright © 2014 The Authors. Arteriosclerosis, Thrombosis, and Vascular Biology is published on behalf of the American Heart Association, Inc., by Wolters
Kluwer. This is an open access article under the terms of the Creative Commons Attribution Non-Commercial License, which permits use, distribution, and
reproduction in any medium, provided that the original work is properly cited and is not used for commercial purposes.
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