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Thesis

Bayesian methods for fine mapping in genetic association studies

Abstract:

Over the past several years genetic variation has been the centre of attention for different branches of genetics. The use of genome wide association studies (GWAS) has facilitated the discovery of a plethora of genetic variants which are associated with a vast range of diseases. These GWAS primarily examine a single variant, mostly a Single Nucleotide Polymorphism (SNP), at a time based on genotype data. Although this practice has proven to be powerful, low percentages of heritability pro...

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Institution:
University of Oxford
Oxford college:
Keble College
Department:
Mathematical,Physical & Life Sciences Division - Statistics
Role:
Author

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Role:
Supervisor
Publication date:
2013
Type of award:
MSc by Research
Level of award:
Masters
Awarding institution:
Oxford University, UK
URN:
uuid:de02203d-6417-45a4-8d95-54960e521e9e
Local pid:
ora:6960

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