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Journal article

Use of schizophrenia and bipolar disorder polygenic risk scores to identify psychotic disorders

Abstract:
Background There is increasing evidence for shared genetic susceptibility between schizophrenia and bipolar disorder. Although genetic variants only convey subtle increases in risk individually, their combination into a polygenic risk score constitutes a strong disease predictor. Aims To investigate whether schizophrenia and bipolar disorder polygenic risk scores can distinguish people with broadly defined psychosis and their unaffected relatives from contro... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1192/bjp.2018.89

Authors


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Grant:
Seventh Framework Programme (602450
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Grant:
MaudsleyNHSFoundationTrust
NIHRBiomedicalResearchCentreattheSouthLondon
InstituteofPsychiatry–KingsCollegeLondon
Publisher:
Cambridge University Press Publisher's website
Journal:
British Journal of Psychiatry Journal website
Volume:
213
Issue:
3
Pages:
535-541
Publication date:
2018-08-16
Acceptance date:
2018-03-13
DOI:
EISSN:
1472-1465
ISSN:
0007-1250
Pmid:
30113282
Source identifiers:
911658
Language:
English
Keywords:
Pubs id:
pubs:911658
UUID:
uuid:de261fca-94da-4049-af00-564e95c05a0b
Local pid:
pubs:911658
Deposit date:
2018-10-30

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