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Thesis

Ionic basis for variability in repolarisaion and its implications in pathological response

Abstract:

Sudden cardiac death represents one of the leading causes of death worldwide, with the majority of these deaths caused by arrhythmias derived from ischæmic events. However, the mechanisms leading from ischæmia to re-entry, arrhythmia and eventual death are poorly understood. Furthermore, variability in the action potential of cardiac tissue, while important in determining arrhythmic risk, is only recently being addressed in computational modelling, with little known about the causes and me...

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Institution:
University of Oxford
Division:
MPLS
Department:
Computer Science
Research group:
Computational Biology
Oxford college:
Oriel College
Role:
Author

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Role:
Supervisor
Role:
Supervisor
Role:
Supervisor
Publication date:
2014
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
Language:
English
Keywords:
Subjects:
UUID:
uuid:dfa89873-abf9-4486-bc9f-dad9f41321fb
Local pid:
ora:11780
Deposit date:
2015-07-02

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