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Thesis

Protein modulation of ion channels

Abstract:

Ion channels lie at the heart of electrical excitability. They represent attractive targets for treatments of a range of pathophysiological conditions, including pain, ischemia and epilepsy. To date, small molecule approaches have dominated ion channel drug discovery, but small molecules often lack the appropriate safety and specificity, ultimately leading to their rejection in the clinic. One way in which to overcome this is to use proteins which use large molecular scaffolds to very precise...

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Division:
MPLS
Department:
Physics
Sub department:
Condensed Matter Physics
Role:
Author

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Role:
Supervisor
Role:
Supervisor
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Programme:
MRC iCASE/ Interdisciplinary Bioscience DTP
Grant:
MR/N017927/1
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
Deposit date:
2022-01-09

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