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In vitro visualization of cell-to-cell interactions between natural killer cells and sensory neurons

Abstract:

Cell-to-cell interactions between the immune and nervous systems are increasingly recognized for their importance in health and disease. Assessment of cellular neuro-immune interactions can be aided by co-culture of two (or more) cells in an in vitro model system that preserves the morphology of neuronal cells. Here we describe methods to investigate the cytotoxic effector functions of natural killer cells on sensory neurons isolated from syngeneic embryonic and adult mice. We present methods...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
ORCID:
0000-0003-0072-1708

Contributors

Role:
Editor
Publisher:
Humana Press Publisher's website
Pages:
251-268
Series:
Methods in Molecular Biology
Series number:
2463
Host title:
Natural Killer (NK) Cells
Chapter number:
18
Publication date:
2022-03-29
DOI:
EISBN:
9781071621608
EISSN:
1940-6029
ISSN:
1064-3745
ISBN:
9781071621592
Language:
English
Keywords:
Subtype:
Chapter
Pubs id:
1249322
Local pid:
pubs:1249322
Deposit date:
2022-04-17

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