Journal article icon

Journal article

Genetic basis of neurocognitive decline and reduced white-matter integrity in normal human brain aging

Abstract:

Identification of genes associated with brain aging should markedly improve our understanding of the biological processes that govern normal age-related decline. However, challenges to identifying genes that facilitate successful brain aging are considerable, including a lack of established phenotypes and difficulties in modeling the effects of aging per se, rather than genes that influence the underlying trait. In a large cohort of randomly selected pedigrees (n = 1,129 subjects), w...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Publisher copy:
10.1073/pnas.1313735110

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
Expand authors...
AT&T Foundation More from this funder
Publisher:
National Academy of Sciences Publisher's website
Journal:
Proceedings of the National Academy of Sciences Journal website
Volume:
110
Issue:
47
Pages:
19006-19011
Publication date:
2013-11-19
DOI:
EISSN:
1091-6490
ISSN:
0027-8424
Source identifiers:
446005
Language:
English
Keywords:
Subjects:
Pubs id:
pubs:446005
UUID:
uuid:e2d435ed-9abf-4741-8a53-a981f75a0e9f
Local pid:
pubs:446005
Deposit date:
2014-01-18

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP