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Thesis

Pharmacoproteomic characterisation of human colon and rectal cancer

Abstract:

Colorectal cancer (CRC) is one of the top three most common cancers and among the top four causes of cancer-related deaths worldwide (Torre et al., 2015). CRC patients are well characterised on the transcriptome and proteome level, but proteomics data on representative cell lines as model systems for pre-clinical drug sensitivity studies lag behind. Here, label-free quantitative mass spectrometry was used to characterise the kinomes and full proteomes of 65 CRC cell lines, collectively ter...

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Institution:
University of Oxford
Oxford college:
Keble College
Role:
Author

Contributors

Department:
Martin-Luther-University Halle-Wittenberg
Role:
Supervisor
Role:
Supervisor
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
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UUID:
uuid:e567791d-c02f-4ccb-9ad3-d6c832500f84
Deposit date:
2017-04-07

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