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Thesis

Characterising the role of circulating immune cells in brain metastasis

Abstract:

Brain metastasis is a frequent occurrence in cancer patients and carries a high mortality rate. The incidence of brain metastasis is on the rise, highlighting the need for improved therapeutic intervention. Immune cells have been shown to promote disseminated tumour cells to colonise the lung and liver. Therefore, we aim to determine whether immune cells also facilitate brain metastasis by describing the host immune response to tumour cells attached to the brain vasculature.

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Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Sub department:
CRUK/MRC Ox Inst for Radiation Oncology
Oxford college:
Lincoln College
Role:
Author

Contributors

Division:
MSD
Department:
Oncology
Sub department:
CRUK/MRC Ox Inst for Radiation Oncology
Role:
Supervisor
More from this funder
Funding agency for:
Balathasan, L
Grant:
"C5255/A9194", "C5255/A15935"
Publication date:
2012
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
UUID:
uuid:e7620d30-7e4a-468b-b819-db4cf27eaef6
Local pid:
ora:8762
Deposit date:
2014-07-11

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