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Thesis

A new level of gene regulation: establishing a genome-wide role for antisense transcription

Abstract:

Transcription lies at the centre of gene expression. In eukaryotes, transcription occurs not only at genes but also across the non-coding portion of the genome, an apparently pervasive process that gives rise to a wide array of different transcripts. In recent years, it has emerged that genes themselves are frequently subject to non-coding transcription of their antisense strand. This antisense transcription is evident in eukaryotes from yeast to mammals; however its general genome-wide ro...

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Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Research group:
Mellor Laboratory
Oxford college:
St John's College
Role:
Author
More by this author
Division:
MSD
Department:
Biochemistry
Role:
Author

Contributors

Division:
MSD
Department:
Biochemistry
Role:
Supervisor
Publication date:
2013
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
Language:
English
Keywords:
Subjects:
UUID:
uuid:e8d4ce6d-f4cf-4a6c-b3c8-f6e16217214b
Local pid:
ora:9673
Deposit date:
2015-01-07

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