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Journal article

Glycosphingolipids Gb3 and iGb3. In vivo roles in hemolytic-uremic syndrome and iNKT cell function

Abstract:: The glycosphingolipids globotrihexosylceramide (Gb3, CD77) and isoglobotrihexosylceramide (iGb3) are isomers differing only in one glycosidic bond and have been implicated in several processes of the innate and adaptive immune system. Aims. 1) To verify the function of Gb3 in the pathogenesis of hemolytic-uremic syndrome as the cellular receptor responsible for cytotoxicity caused by verotoxin (VT) elaborated by Shigella and certain strains of E.coli. 2) To investigate in vivo the previously ...
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APA Style

Porubsky, S., Luckow, B., Bonrouhi, M., Speak, A., Cerundolo, V., Platt, F., & Gröne, H. (2008). Glycosphingolipids Gb3 and iGb3. In vivo roles in hemolytic-uremic syndrome and iNKT cell function. Pathologe, 29(SUPPL. 2), 297–302.

MLA Style

Porubsky, S., et al. “Glycosphingolipids Gb3 and iGb3. In Vivo Roles in Hemolytic-Uremic Syndrome and INKT Cell Function.” Pathologe, vol. 29, no. SUPPL. 2, 2008, pp. 297–302.

Chicago Style

Porubsky, S, B Luckow, M Bonrouhi, A Speak, V Cerundolo, F Platt, and H Gröne. 2008. “Glycosphingolipids Gb3 and iGb3. In Vivo Roles in Hemolytic-Uremic Syndrome and INKT Cell Function.” Pathologe 29 (SUPPL. 2): 297–302.
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Publisher copy:: 10.1007/s00292-008-1040-0

Authors

+ Porubsky, S More by this author

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+ Luckow, B More by this author

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+ Bonrouhi, M More by this author

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+ Speak, A More by this author

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+ Cerundolo, V More by this author

Institution:

University of Oxford

Division:

MSD

Department:

RDM

Sub department:

Weatherall Insti. of Molecular Medicine

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Bibliographic Details

Journal:: Pathologe
Volume:: 29
Issue:: SUPPL. 2
Pages:: 297-302
Publication date:: 2008-11-01
DOI:: 10.1007/s00292-008-1040-0
ISSN:: 0172-8113

Item Description

Language:: German
Keywords:: iGb3

HUS-TTP

Gb3

iNKT
Pubs id:: pubs:96047
UUID:: uuid:ec3004fd-990a-40a7-b58b-6fa3add320fa
Local pid:: pubs:96047
Source identifiers:: 96047
Deposit date:: 2012-12-19

Terms of use

Copyright date:: 2008

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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