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Journal article

Human genetics of obesity and type 2 diabetes mellitus: past, present, and future

Abstract:

Type 2 diabetes mellitus (T2D) and obesity already represent 2 of the most prominent risk factors for cardiovascular disease, and are destined to increase in importance given the global changes in lifestyle. Ten years have passed since the first round of genome-wide association studies for T2D and obesity. During this decade, we have witnessed remarkable developments in human genetics. We have graduated from the despair of candidate gene-based studies that generated few consistently replicate...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1161/CIRCGEN.118.002090

Authors


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Institution:
University of Oxford
Division:
Medical Science Division
Department:
RDM; RDM Strategic
Oxford college:
Green Templeton College
Role:
Author
ORCID:
0000-0002-4393-0510
More from this funder
Funding agency for:
Ingelsson, E
Grant:
1R01HL135313-01
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Funding agency for:
McCarthy, M
Grant:
U01DK105535
Publisher:
American Heart Association Publisher's website
Journal:
Circulation: Genomic and Precision Medicine Journal website
Volume:
11
Issue:
6
Article number:
e002090
Publication date:
2018-06-13
DOI:
ISSN:
2574-8300
Pmid:
29899044
Source identifiers:
857280
Language:
English
Keywords:
Pubs id:
pubs:857280
UUID:
uuid:ec41fcde-75b7-4694-a2d1-a6398e0dbc3b
Local pid:
pubs:857280
Deposit date:
2018-07-09

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