Journal article
Variation in structural location and amino acid conservation of functional sites in protein domain families
- Abstract:
-
Background: The functional sites of a protein present important information for determining its cellular function and are fundamental in drug design. Accordingly, accurate methods for the prediction of functional sites are of immense value. Most available methods are based on a set of homologous sequences and structural or evolutionary information, and assume that functional sites are more conserved than the average. In the analysis presented here, we have investigated the conservation of loc...
Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Access Document
- Files:
-
-
(pdf, 1.0MB)
-
- Publisher copy:
- 10.1186/1471-2105-6-210
Why is the content I wish to access not available via ORA?
Bibliographic data (the information relating to research outputs) and full-text items (e.g. articles, theses, reports, etc.) arrive in ORA from several different sources. Unfortunately we are not able to make available the full-text for every research output.
Please contact the ORA team (
) if you have queries regarding unavailable content OR if you are aware of a full-text copy we can make available.
) if you have queries regarding unavailable content OR if you are aware of a full-text copy we can make available.
Content may be unavailable for the following four reasons
-
Version unsuitable
-
We have not obtained a suitable full-text for a given research output. See this page for more information.
-
Recently completed
-
Sometimes content is held in ORA but is unavailable for a fixed period of time to comply with the policies and wishes of rights holders.
-
Permissions
-
All content made available in ORA should comply with relevant rights, such as copyright. See this page for more information.
-
Clearance
-
Some thesis volumes scanned as part of the digitisation scheme funded by Dr Leonard Polonsky are currently unavailable due to sensitive material or uncleared third-party copyright content. We are attempting to contact authors whose theses are affected.
Alternative access to the full-text
You may be able to access the full-text directly from the publisher's website using the 'Publisher Copy' link in the 'Links & Downloads' box from a research output's ORA record page. This method may require an institutional or individual subscription to the journal/resource.
Authors
Funding
Bibliographic Details
- Publisher:
- BioMed Central
- Journal:
- BMC Bioinformatics Journal website
- Volume:
- 6
- Article number:
- 210
- Publication date:
- 2005-01-01
- DOI:
- ISSN:
-
1471-2105
Item Description
- Language:
- English
- Subjects:
- UUID:
-
uuid:ed0a1189-d699-4839-b227-c49308b43385
- Local pid:
- ora:2285
- Deposit date:
- 2008-09-04
Related Items
Terms of use
- Copyright holder:
- Pils et al
- Copyright date:
- 2005
- Notes:
-
Citation: Pils, B. & Copley, R. R. & Schultz, J. (2005). 'Variation in structural location and amino acid conservation of functional sites in protein domain families', BMC Bioinformatics, 6:210. [Available at http://www.biomedcentral.com/1471-2105/6/210]
Copyright 2005 Pils et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
If you are the owner of this record, you can report an update to it here: Report update to this record