Thesis
Regulation of IRF5 activity in inflammatory diseases: novel kinases
- Abstract:
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Interferon regulatory factor 5 (IRF5), is a multifunctional regulator of immune responses, with a critical role in controlling pro-inflammatory responses of macrophages. IRF5 contributes to the pathogenesis of several inflammatory and autoimmune diseases. Given the importance of IRF5 function in physiology and disease, IRF5 represents a therapeutic target. However, the mechanisms regulating IRF5 activation and the kinases responsible for its phosphorylation in vivo have been unclear. The p...
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Funding
Bibliographic Details
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:efca1630-8eb8-4195-abc8-4f16ff468bf0
- Deposit date:
- 2020-02-25
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Terms of use
- Copyright holder:
- Almuttaqi, H
- Copyright date:
- 2019
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