Journal article
Structure of the Plasmodium falciparum heat shock protein 70-x substrate binding domain
- Abstract:
-
The malaria parasite Plasmodium falciparum extensively modifies erythrocytes that it invades by exporting a large complement of proteins to the host cell. Among these exported components is a single heat-shock 70 kDa class protein, PfHsp70-x, that supports the virulence and growth rate of the parasite during febrile episodes. The ATP-binding domain of PfHsp70-x has previously been resolved and showed the presence of potentially druggable epitopes that differ from those on human Hsp70 chaperon...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Funding
Bibliographic Details
- Publisher:
- International Union of Crystallography Publisher's website
- Journal:
- Acta Crystallographica Section F: Structural Biology Communications Journal website
- Volume:
- F76
- Pages:
- 495-500
- Publication date:
- 2020-09-29
- Acceptance date:
- 2020-09-01
- DOI:
- EISSN:
-
2053-230X
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
1129585
- Local pid:
- pubs:1129585
- Deposit date:
- 2020-09-01
Terms of use
- Copyright holder:
- Schmidt and Vakonakis
- Copyright date:
- 2020
- Rights statement:
- © The Author(s) 2020. Open Access: This article is licensed under a Creative Commons Attribution 4.0 International License.
- Licence:
- CC Attribution (CC BY)
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