Journal article
Characterization of human papillomavirus (HPV) 16 E6 seropositive individuals without HPV-associated malignancies after 10 years of follow-up in the UK Biobank
- Abstract:
-
Background Antibodies against the HPV16 oncoprotein E6 are promising biomarkers for HPV16-driven oropharyngeal cancer (HPV16-OPC) due to their high sensitivity and specificity, and prospective manifestation. In previous studies, 0•7% of controls without HPV-associated malignancies were HPV16 E6 seropositive of which only a minority is expected to develop HPV16-driven cancer. We aimed to characterise HPV16 E6 antibodies in individuals without HPV-associated malignancies. Methods We analysed s...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Authors
Funding
Medical Research Council
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Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- EBioMedicine Journal website
- Volume:
- 62
- Article number:
- 103123
- Publication date:
- 2020-11-25
- Acceptance date:
- 2020-10-28
- DOI:
- EISSN:
-
2352-3964
- Pmid:
-
33248371
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
1148373
- Local pid:
- pubs:1148373
- Deposit date:
- 2021-06-02
Terms of use
- Copyright holder:
- Brenner et al.
- Copyright date:
- 2020
- Rights statement:
- © 2020 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
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