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Emergence of double- and triple-gene reassortant G1P[8] rotaviruses possessing a DS-1-Like backbone after rotavirus vaccine introduction in Malawi

Abstract:

To combat the high burden of rotavirus gastroenteritis, multiple African countries have introduced rotavirus vaccines into their childhood immunization programs. Malawi incorporated a G1P[8] rotavirus vaccine (Rotarix) into its immunization schedule in 2012. Utilizing a surveillance platform of hospitalized rotavirus gastroenteritis cases, we examined the phylodynamics of G1P[8] rotavirus strains that circulated in Malawi before (1998 to 2012) and after (2013 to 2014) vaccine introduction. An...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1128/jvi.01246-17

Authors


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Role:
Author
ORCID:
0000-0003-3376-8529
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Role:
Author
ORCID:
0000-0002-2108-1757
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Role:
Author
ORCID:
0000-0003-0570-4624
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Contributors

Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Contributor
ORCID:
0000-0002-5923-9468
Wellcome Trust More from this funder
Publisher:
American Society for Microbiology Publisher's website
Journal:
Journal of Virology Journal website
Volume:
92
Issue:
3
Publication date:
2018-01-17
Acceptance date:
2017-11-03
DOI:
EISSN:
1098-5514
ISSN:
0022-538X
Pmid:
29142125
Language:
English
Keywords:
Pubs id:
1084492
Local pid:
pubs:1084492
Deposit date:
2020-06-24

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