Mathematical approaches to modelling healing of full thickness circular skin wounds

Thesis

Wound healing is a complex process, in which a sequence of interrelated events at both the cell and tissue levels interact and contribute to the reduction in wound size. For diabetic patients, many of these processes are compromised, so that wound healing slows down and in some cases halts. In this thesis we develop a series of increasingly detailed mathematical models to describe and investigate healing of full thickness skin wounds.

We begin by developing a time-dependent ordinary...

Expand abstract

Authors: Bowden, L

• Publication date: 2015
• Type of award: DPhil
• Level of award: Doctoral
• Awarding institution: University of Oxford
• Language: English
• Keywords: finite elasticity; epidermis; contraction; dermis; growth; wound healing
• Subjects: Mathematical biology; Biology and other natural sciences (mathematics); Life Sciences; Mechanics of deformable solids (mathematics); Diabetes; Partial differential equations; Biology; Ordinary differential equations; Mathematics