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Journal article

Why some tumours trigger neovascularisation and others don’t: the story thus far

Abstract:

Background Angiogenesis is not essential for tumours to develop and expand, as cancer can also grow in a non-angiogenic fashion, but why this type of growth occurs is unknown. Surprisingly, our data from mRNA transcription profiling did not show any differences in the classical angiogenic pathways, but differences were observed in mitochondrial metabolic pathways, suggesting a key role for metabolic reprogramming. We then validated these results with mRNA profiling by investigating differenti...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1186/s40880-016-0082-6

Authors


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Medical Research Council More from this funder
Cancer Research UK More from this funder
Publisher:
BioMed Central Publisher's website
Journal:
Chinese Journal of Cancer Journal website
Volume:
35
Issue:
1
Pages:
18
Publication date:
2016-02-12
Acceptance date:
2015-12-20
DOI:
EISSN:
1944-446X
ISSN:
1000-467X
Pmid:
26873439
Source identifiers:
605207
Language:
English
Keywords:
Pubs id:
pubs:605207
UUID:
uuid:f2a6dfa1-7ea0-4965-9aee-e2fdc97a75cc
Local pid:
pubs:605207
Deposit date:
2017-06-14

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