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Thesis

Utilisation of enzymes as powerful tools towards fluorinated biomolecules

Abstract:

Incorporation of fluorine into biomolecules provides versatile opportunities for clinical and pre-clinical imaging, with 18F-PET and 19F-MRI and as reporter tags for “zero-background” 19F-NMR. Considerable effort has been made towards achieving direct fluorination of biomolecules, however nucleophilic fluorination methods typically require anhydrous conditions and organic solvents, while electrophilic methods suffer from high reactivity of fluorine gas and ...

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Division:
MPLS
Department:
Chemistry
Role:
Author

Contributors

Role:
Supervisor
Role:
Supervisor
ORCID:
0000-0001-8638-5308
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Subjects:
Deposit date:
2021-08-27

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