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Thesis

The centriole in evolution: from motility to mitosis

Abstract:

Centrioles and basal bodies with their characteristic 9+2 structure are found in all major eukaryotic lineages. The correlation between the occurrence of centrioles and the presence of cilia/flagella, but not centrosome-like structures, suggests that the ciliogenesis function of centrioles is ancestral. Here, it is demonstrated that the centriole domain of centrosomes emerged within the Metazoa from an ancestral state of possessing a centriole with basal body function but no funct...

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Institution:
University of Oxford
Division:
MPLS
Department:
Zoology
Oxford college:
Merton College
Role:
Author

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Division:
MPLS
Department:
Zoology
Role:
Supervisor
Publication date:
2013
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
Language:
English
Keywords:
Subjects:
UUID:
uuid:f48e77ea-fbf9-4ac6-b86e-854f6739a5aa
Local pid:
ora:11851
Deposit date:
2015-07-10

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