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Thesis

Epigenetic regulation of the myeloid cell lineage

Abstract:

The myeloid cell lineage is a fundamental element of the immune system and it can give rise to a diverse set of terminally differentiated cells, such as macrophages or osteoclasts among many others. Mutations or misregulation of gene expression may lead to severe clinical conditions, such as arthritis, osteoporosis or cancers. Epigenetics, the regulation of gene expression and chromatin remodelling, is implicated in cell differentiation, function and disease, and hence it is a promising ne...

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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Research group:
Professor Udo Oppermann
Oxford college:
Pembroke College
Role:
Author

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Role:
Supervisor
Role:
Supervisor
Role:
Supervisor
Role:
Supervisor
Publication date:
2014
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
UUID:
uuid:f4ee6659-ce0b-4730-ae5b-95c141f82e10
Local pid:
ora:11574
Deposit date:
2015-06-04

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