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Allele specific gene expression in the major histocompatibility complex

Abstract:

The Major Histocompatibility Complex (MHC) is a highly polymorphic region of the genome located on chromosome 6p21 in which genetic diversity has been associated with susceptibility to many autoimmune, infectious and other common diseases. Despite strong associations between disease and variation in the MHC that have been identified initially from serological testing and more recently by genome-wide association studies, functional insights into how specific variants may be altering diseas...

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Research group:
Julian Knight
Oxford college:
Jesus College
Role:
Author

Contributors

Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Role:
Supervisor
Publication date:
2012
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
UUID:
uuid:f565a41c-4699-4416-b1be-150b6a87dd0f
Local pid:
ora:6387
Deposit date:
2012-07-20

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