Journal article
Pcsk5 is required in the early cranio-cardiac mesoderm for heart development.
- Abstract:
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Background
Loss of proprotein convertase subtilisin/kexin type 5 (Pcsk5) results in multiple developmental anomaliesincluding cardiac malformations, caudal regression, pre-sacral mass, renal agenesis, anteroposterior patterning defects, and tracheo-oesophageal and anorectal malformations, and is a model for VACTERL/caudal regression/Currarino syndromes (VACTERL association - Vertebral anomalies, Anal atresia, Cardiac defects, Tracheoesophageal fistula and/or Esophageal atresia, R...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(pdf, 4.4MB)
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- Publisher copy:
- 10.1186/s12861-017-0148-y
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Authors
Funding
Bibliographic Details
- Publisher:
- BioMed Central Publisher's website
- Journal:
- BMC Developmental Biology Journal website
- Volume:
- 17
- Issue:
- 1
- Pages:
- 6
- Publication date:
- 2017-04-01
- Acceptance date:
- 2017-04-17
- DOI:
- ISSN:
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1471-213X
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:692368
- UUID:
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uuid:f797bee9-e00c-43fd-a4c0-ae0a8bb131e2
- Local pid:
- pubs:692368
- Deposit date:
- 2017-07-10
Terms of use
- Copyright holder:
- Bhattacharya et al
- Copyright date:
- 2017
- Notes:
- © The Author(s). 2017 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
- Licence:
- CC Attribution (CC BY)
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