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Thesis

Implications of HCV genotype 3 specific immunity on cross-reactive vaccine design

Abstract:

Hepatitis C virus (HCV) is a major global pathogen that infects an estimated 170 million people worldwide, and for which currently no vaccine is available. HCV is a highly diverse viral pathogen and exists as 6 major genotypes sharing only 75% sequence homology; developing a vaccine that is cross-reactive between genotypes is a major challenge. Defining immune responses that target different HCV genotypes will facilitate pan-genotypic T cell vaccine development.

HCV genotype 3 (gt3)...

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Institution:
University of Oxford
Division:
MSD
Oxford college:
Christ Church
Role:
Author

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Role:
Supervisor
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Funding agency for:
von Delft, A
Publication date:
2014
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
Language:
English
Keywords:
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UUID:
uuid:f7daefac-3f4d-4040-ac6f-52c476d527be
Local pid:
ora:11931
Deposit date:
2015-07-28

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