Thesis
Implications of HCV genotype 3 specific immunity on cross-reactive vaccine design
- Abstract:
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Hepatitis C virus (HCV) is a major global pathogen that infects an estimated 170 million people worldwide, and for which currently no vaccine is available. HCV is a highly diverse viral pathogen and exists as 6 major genotypes sharing only 75% sequence homology; developing a vaccine that is cross-reactive between genotypes is a major challenge. Defining immune responses that target different HCV genotypes will facilitate pan-genotypic T cell vaccine development.
HCV genotype 3 (gt3)...
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Funding
Bibliographic Details
- Publication date:
- 2014
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- Oxford University, UK
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
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uuid:f7daefac-3f4d-4040-ac6f-52c476d527be
- Local pid:
- ora:11931
- Deposit date:
- 2015-07-28
Terms of use
- Copyright holder:
- Annette von Delft
- Copyright date:
- 2014
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