Journal article
Dictyostelium as a model to assess site-specific ADP-ribosylation events
- Abstract:
-
The amoeba Dictyostelium discoideum is a single-cell organism that can undergo a simple developmental program, making it an excellent model to study the molecular mechanisms of cell motility, signal transduction, and cell-type differentiation. A variety of human genes that are absent or show limited conservation in other invertebrate models have been identified in this organism. This includes ADP-ribosyltransferases, also known as poly-ADP-ribose polymerases (PARPs), a family of proteins that...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
+ National Centre for the Replacement, Refinement and Reduction of Animals in Research
More from this funder
Funding agency for:
Pears, CJ
Grant:
NC/M000834/1
NC/K00137X/1
Bibliographic Details
- Publisher:
- Springer Verlag Publisher's website
- Journal:
- Methods in Molecular Biology Journal website
- Volume:
- 1813
- Pages:
- 125-148
- Publication date:
- 2018-08-11
- DOI:
- ISSN:
-
1064-3745 and 1940-6029
- Pmid:
-
30097865
- ISBN:
- 9781493985876
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:909911
- UUID:
-
uuid:fa8bd0d1-f81d-4b80-8ddf-4f380c5ba283
- Local pid:
- pubs:909911
- Deposit date:
- 2018-11-13
Terms of use
- Copyright holder:
- Springer Science+Business Media, LLC, part of Springer Nature
- Copyright date:
- 2018
- Notes:
- © Springer Science+Business Media, LLC, part of Springer Nature 2018.
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