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Journal article

Immunogenicity of standard and extended dosing intervals of BNT162b2 mRNA vaccine

Abstract:

Extension of the interval between vaccine doses for the BNT162b2 mRNA vaccine was introduced in the United Kingdom to accelerate population coverage with a single dose. At this time, trial data were lacking, and we addressed this in a study of United Kingdom healthcare workers. The first vaccine dose induced protection from infection from the circulating alpha (B.1.1.7) variant over several weeks. In a substudy of 589 individuals, we show that this single dose induces severe acute respiratory...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.cell.2021.10.011

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Role:
Contributor
Wellcome Trust More from this funder
Publisher:
Cell Press Publisher's website
Journal:
Cell Journal website
Volume:
184
Issue:
23
Pages:
5699-5714
Publication date:
2021-10-16
Acceptance date:
2021-10-12
DOI:
EISSN:
1097-4172
ISSN:
0092-8674
Language:
English
Keywords:
Pubs id:
1206297
Local pid:
pubs:1206297
Deposit date:
2021-11-09

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