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Thesis

Cardiac resynchronisation therapy and myocardial metabolism: acute and chronic effects in heart failure

Abstract:

Since its development in the 1990s, cardiac resynchronisation therapy has evolved to occupy a key position in the management of heart failure with a reduced ejection fraction and broadened QRS duration, inducing both acute haemodynamic improvements as well as chronic reverse remodelling. However, approximately 30% of patients appear to not respond to CRT. Whilst factors such as heart failure aetiology and patient comorbidity, e.g. diabetes mellitus, have been shown to correlate with poor...

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Division:
MSD
Department:
Physiology Anatomy & Genetics
Oxford college:
Keble College
Role:
Author

Contributors

Institution:
University of Oxford
Division:
MSD
Department:
RDM
Role:
Contributor
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Role:
Contributor
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Role:
Contributor
ORCID:
0000-0003-2567-3642
Institution:
Oxford University Hospitals NHS Foundation Trust
Role:
Contributor
Institution:
Oxford University Hospitals NHS Foundation Trust
Role:
Contributor
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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