Journal article
Allelic association with ankylosing spondylitis fails to correlate with human leukocyte antigen B27 homodimer formation
- Abstract:
-
Expression of human leukocyte antigen (HLA)-B27 is strongly associated with predisposition toward ankylosing spondylitis (AS) and other spondyloarthropathies. However, the exact involvement of HLA-B27 in disease initiation and progression remains unclear. The homodimer theory, which proposes that HLA-B27 heavy chains aberrantly form homodimers, is a central hypothesis that attempts to explain the role of HLA-B27 in disease pathogenesis. Here, we examined the ability of the eight most prevalen...
Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Authors
Bibliographic Details
- Publisher:
- American Society for Biochemistry and Molecular Biology Publisher's website
- Journal:
- Journal of Biological Chemistry Journal website
- Volume:
- 294
- Issue:
- 52
- Pages:
- 20185-20195
- Publication date:
- 2019-11-18
- Acceptance date:
- 2019-11-18
- DOI:
- EISSN:
-
1083-351X
- ISSN:
-
0021-9258
- Pmid:
-
31740583
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
1074801
- Local pid:
- pubs:1074801
- Deposit date:
- 2020-03-05
Terms of use
- Copyright holder:
- Lim Kam Sian et al.
- Copyright date:
- 2019
- Rights statement:
- © 2019 Lim Kam Sian et al. Published under exclusive license by The American Society for Biochemistry and Molecular Biology, Inc.
Metrics
If you are the owner of this record, you can report an update to it here: Report update to this record