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DNA testing for hypertrophic cardiomyopathy: a cost-effectiveness model

Abstract:

Aims: To explore the cost-effectiveness of alternative methods of screening family members for hypertrophic cardiomyopathy (HCM), the most common monogenic cardiac disorder and the most frequent cause of sudden cardiac death (SCD) in young people.

Methods and results: Economic decision model comparing cascade screening by genetic, as opposed to clinical methods. The incremental cost per life year saved was €14 397 for the cascade genetic compared with the cascade clinical approach. G...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/eurheartj/ehq067

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Research group:
Health Economics Research Centre
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Research group:
Health Economics Research Centre
Role:
Author
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Institution:
"Churchill Hospital, Oxford, UK", "University of Oxford"
Department:
Medical Sciences Division - Cardiovascular Medicine
Role:
Author
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Institution:
London School of Hygiene and Tropical Medicine, London, UK
Department:
Health Services Research Unit
Role:
Author
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Institution:
"Churchill Hospital, Oxford, UK"
Department:
Molecular Genetics Laboratory
Role:
Author
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Contributors

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Funding agency for:
Wordsworth, S
UK Department of Health More from this funder
Publisher:
Oxford University Press Publisher's website
Journal:
European Heart Journal Journal website
Volume:
31
Issue:
8
Pages:
926-935
Publication date:
2010-01-01
DOI:
EISSN:
1522-9645
ISSN:
0195-668x
Language:
English
Keywords:
Subjects:
UUID:
uuid:fdcd9187-4fdf-48dd-8b4f-330e53718f14
Local pid:
ora:5535
Deposit date:
2011-07-06

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