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P. falciparum infection and maternofetal antibody transfer in malaria-endemic settings of varying transmission

Abstract:

During pregnancy, immunoglobulin G (IgG) is transferred from the mother to the fetus, providing protection from disease in early infancy. Plasmodium falciparum infections may reduce maternofetal antibody transfer efficiency, but mechanisms remain unclear.Mother-cord paired serum samples collected at delivery from Papua New Guinea (PNG) and the Thailand-Myanmar Border Area (TMBA) were tested for IgG1 and IgG3 to four P. falciparum antigens and measles antigen, as well as total serum IgG. Multi...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.pone.0186577

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
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Publisher:
Publisher Library of Science Publisher's website
Journal:
PloS one Journal website
Volume:
12
Issue:
10
Pages:
e0186577
Publication date:
2017-10-13
Acceptance date:
2017-10-03
DOI:
ISSN:
1932-6203
Pmid:
29028827
Source identifiers:
737246
Language:
English
Keywords:
Subjects:
Pubs id:
pubs:737246
UUID:
uuid:ff042ebf-b2a9-446f-96ee-b2ca2e20cc2e
Local pid:
pubs:737246
Deposit date:
2017-10-27

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