Thesis
Characterisation of the transcriptomes of Leishmania mexicana promastigotes and amastigotes
- Abstract:
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Leishmania spp. undergo substantial adaptations from being promastigotes, found in sandflies, to being amastigotes, residing in parasitophorous vacuoles within mammalian macrophages. In the past, microarray studies have sought to elucidate these adaptations using axenic amastigote systems or amastigotes purified from host-cells, raising the question whether the observed transcriptomic signatures were a true reflection of intracellular amastigotes. Moreover, with ever-improving gen...
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Authors
Contributors
+ Gluenz, E
Division:
MSD
Department:
Pathology Dunn School
Role:
Supervisor
+ Gull, K
Division:
MSD
Department:
Pathology Dunn School
Role:
Supervisor
Funding
Bibliographic Details
- Publication date:
- 2014
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- Oxford University, UK
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:ff1a5033-e1a4-40cc-8204-7de904ba7aa2
- Local pid:
- ora:11850
- Deposit date:
- 2015-07-10
Terms of use
- Copyright holder:
- Fiebig, M
- Copyright date:
- 2014
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